Pierre Lachapelle Selected Research

Arachidonic Acids

1/2011	Understanding retinopathy of prematurity: update on pathogenesis.
2/2010	Understanding ischemic retinopathies: emerging concepts from oxygen-induced retinopathy.

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Pierre Lachapelle Research Topics

Disease

7	Hyperoxia 12/2018 - 07/2002
6	Retinopathy of Prematurity (Retrolental Fibroplasia) 12/2016 - 07/2002
5	Hypoxia (Hypoxemia) 12/2016 - 02/2010
4	Diabetic Retinopathy (Retinopathy, Diabetic) 06/2019 - 01/2005
4	Ischemia 01/2016 - 06/2006
3	congenital stationary Night blindness 10/2020 - 07/2003
3	Retinal Neovascularization 01/2011 - 04/2006
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 06/2019 - 07/2003
2	Blindness (Hysterical Blindness) 01/2019 - 12/2016
2	Inflammation (Inflammations) 12/2013 - 02/2003
2	Pathologic Neovascularization 04/2012 - 07/2011
2	Platelet Glycoprotein IV Deficiency 12/2010 - 02/2008
2	Ganglion Cysts (Ganglion) 10/2008 - 07/2008
2	Retinal Degeneration 02/2008 - 09/2005
2	Retinal Vein Occlusion 05/2005 - 01/2005
1	Peroxisome biogenesis disorders 12/2021
1	Amblyopia (Lazy Eye) 01/2021
1	Macular Degeneration (Age-Related Maculopathy) 06/2019
1	Zellweger Syndrome (Zellweger's Syndrome) 01/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2018
1	Foreign Bodies (Foreign Body) 10/2017
1	Brain Injuries (Brain Injury) 08/2015
1	Brain Diseases (Brain Disorder) 08/2015
1	Vision Disorders (Hemeralopia) 08/2015
1	Wounds and Injuries (Trauma) 08/2015
1	Vascular Diseases (Vascular Disease) 06/2014
1	Aortic Coarctation 06/2014
1	Sepsis (Septicemia) 12/2013
1	Methylenetetrahydrofolate reductase deficiency 02/2011
1	Homocystinuria 02/2011
1	Seizures (Absence Seizure) 02/2011
1	Thrombocytopenia (Thrombopenia) 02/2011
1	Atrophy 02/2008
1	Photophobia (Light Sensitivity) 10/2007
1	Microvascular Rarefaction 03/2007
1	Leber Congenital Amaurosis 09/2006
1	Hypercapnia 06/2006
1	Necrosis 10/2002
1	Shock 07/2002
1	Seasonal Affective Disorder 04/2002

Drug/Important Bio-Agent (IBA)

31	Retinaldehyde (Retinal)IBA 12/2021 - 04/2002
9	Oxygen (Dioxygen)IBA 01/2016 - 07/2002
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2012 - 02/2008
3	Succinic Acid (Succinate)IBA 01/2011 - 10/2008
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 04/2006
2	LipidsIBA 01/2011 - 02/2003
2	Arachidonic AcidsIBA 01/2011 - 02/2010
1	Estradiol (Delestrogen)FDA LinkGeneric 12/2018
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2016
1	Sildenafil Citrate (Viagra)FDA Link 01/2016
1	LipopolysaccharidesIBA 12/2013
1	Endothelial Growth FactorsIBA 04/2012
1	GhrelinIBA 07/2011
1	HomocysteineIBA 02/2011
1	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 02/2011
1	Semaphorins (Semaphorin)IBA 01/2011
1	oxidized low density lipoproteinIBA 12/2010
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 05/2009
1	Ciliary Neurotrophic Factor (CNTF)IBA 05/2009
1	Scavenger Receptors (Scavenger Receptor)IBA 02/2008
1	SB 203580IBA 03/2007
1	pyrazolanthroneIBA 03/2007
1	Arachidonic Acid (Vitamin F)IBA 06/2006
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 06/2006
1	Fc Receptors (Fc Receptor)IBA 04/2006
1	Neutralizing AntibodiesIBA 04/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2006
1	Infliximab (Remicade)FDA Link 04/2006
1	Etanercept (Enbrel)FDA Link 04/2006
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 04/2006
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 04/2006
1	Vitamin E FDA LinkGeneric 03/2006
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 03/2006
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 09/2005
1	Malondialdehyde (Propanedial)IBA 12/2004
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 12/2004
1	Glutathione (Reduced Glutathione)IBA 12/2004
1	3-nitrotyrosineIBA 12/2004
1	copper bis(3,5-diisopropylsalicylate)IBA 12/2004
1	ProstaglandinsIBA 02/2003
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 10/2002
1	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 10/2002
1	Niacinamide (Nicotinamide)FDA LinkGeneric 10/2002
1	Caspase InhibitorsIBA 10/2002
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2002
1	benzoylcarbonyl- aspartyl- glutamyl- valyl- aspartyl- fluoromethyl ketoneIBA 10/2002

Therapy/Procedure

2	Ligation 01/2016 - 08/2015
1	Therapeutics 12/2021
1	Electrodes (Electrode) 10/2017
1	Intraperitoneal Injections 12/2013
1	Injections 03/2006